Frequently asked questions on longevity and ageing

In the narrow sense: a high age with preserved health and quality of life. Often a distinction is made between lifespan (total length of life) and healthspan (years in good health). In research the focus is on mechanisms of ageing and factors that affect both.

An estimate of how “old” the body appears compared to chronological age – often based on biomarkers (e.g. epigenetic clocks). It is not an exact value and does not replace medical assessment.

Models that estimate an age from DNA methylation patterns. They correlate in studies with disease risk and mortality but capture only one part of ageing processes. Commercial tests should be viewed critically.

In animal models and some short human studies there are effects on metabolism and biomarkers. Long-term controlled studies in humans on lifespan are lacking. For some people intermittent fasting is unsuitable (e.g. with eating disorders). Not a substitute for a balanced diet and medical advice.

Exercise is consistently associated in observational studies with better health and longer life expectancy. The evidence is clearly stronger than for most “longevity” supplements. Type and amount should suit the person; clarify with a doctor if you have existing conditions.

The evidence is mixed. Some substances are studied in research; for everyday use long-term studies and clear benefit-risk assessments are often missing. Interactions and overdose need to be considered. Not a substitute for proven prevention.

Currently not in the sense of a stop. Certain lifestyle factors and medical progress can positively affect health and life expectancy. “Anti-ageing” promises that claim more are not evidence-based.

Reliability varies. Some tests are based on scientific models but are not sufficiently validated for individual prognosis. Others are mainly marketing. Results should not be overinterpreted and ideally discussed with a doctor.

The term is misleading. No approved “treatment” has been shown to rejuvenate humans. Some procedures (e.g. certain therapies in trials) target biomarkers or partial aspects; long-term effects and safety are often unclear. Be cautious with expensive offers without clear evidence.

No. Human Longevity is an information project only. We do not give diagnoses, treatment recommendations or individual advice. For health questions please contact a doctor.

No. We do not sell supplements, tests or other products. There are no affiliate links to longevity providers. The project is not funded by product recommendations.